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A benzimidazole inhibitor attenuates sterile inflammation induced in a model of systemic autoinflammation in female mice

Sterile stimuli can trigger inflammatory responses, and in some cases can lead to a variety of acute or chronic diseases. In this study, we hypothesize that a benzimidazole inhibitor may be used as a therapeutic in the treatment of sterile inflammation. In vitro, this inhibitor blocks TLR signalling...

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Detalles Bibliográficos
Autores principales: Agliano, Federica, Karlinsey, Keaton S., Ragazzi, Michael, Ménoret, Antoine, Vella, Anthony T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7374700/
https://www.ncbi.nlm.nih.gov/pubmed/32694575
http://dx.doi.org/10.1038/s41598-020-68985-1