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Circulatory and prostatic tissue lipidomic profiles shifts after high-dose atorvastatin use in men with prostate cancer

Prostate cancer patients using cholesterol-lowering statins have 30% lower risk of prostate cancer death compared to non-users. The effect is attributed to the inhibition of the mevalonate pathway in prostate cancer cells. Moreover, statin use causes lipoprotein metabolism changes in the serum. Stat...

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Detalles Bibliográficos
Autores principales: Raittinen, Paavo, Niemistö, Kati, Pennanen, Erika, Syvälä, Heimo, Auriola, Seppo, Riikonen, Jarno, Lehtimäki, Terho, Ilmonen, Pauliina, Murtola, Teemu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7374714/
https://www.ncbi.nlm.nih.gov/pubmed/32694638
http://dx.doi.org/10.1038/s41598-020-68868-5