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Translating current basic research into future therapies for neurofibromatosis type 1

Neurofibromatosis type 1 (NF1) is a hereditary tumour syndrome that predisposes to benign and malignant tumours originating from neural crest cells. Biallelic inactivation of the tumour-suppressor gene NF1 in glial cells in the skin, along a nerve plexus or in the brain results in the development of...

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Detalles Bibliográficos
Autores principales: Brosseau, Jean-Philippe, Liao, Chung-Ping, Le, Lu Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7374719/
https://www.ncbi.nlm.nih.gov/pubmed/32439933
http://dx.doi.org/10.1038/s41416-020-0903-x