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Elucidating the mechanisms by which disulfiram protects against obesity and metabolic syndrome

There is an unmet need and urgency to find safe and effective anti-obesity interventions. Our recent study in mice fed on obesogenic diet found that treatment with the alcohol aversive drug disulfiram reduced feeding efficiency and led to a decrease in body weight and an increase in energy expenditu...

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Detalles Bibliográficos
Autores principales: Bernier, Michel, Harney, Dylan, Koay, Yen Chin, Diaz, Antonio, Singh, Abhishek, Wahl, Devin, Pulpitel, Tamara, Ali, Ahmed, Guiterrez, Vince, Mitchell, Sarah J., Kim, Eun-Young, Mach, John, Price, Nathan L., Aon, Miguel A., LeCouteur, David G., Cogger, Victoria C., Fernandez-Hernando, Carlos, O’Sullivan, John, Larance, Mark, Cuervo, Ana Maria, de Cabo, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7374720/
https://www.ncbi.nlm.nih.gov/pubmed/32714562
http://dx.doi.org/10.1038/s41514-020-0046-6