Computational analysis of androgen receptor (AR) variants to decipher the relationship between protein stability and related-diseases

Although more than 1,000 androgen receptor (AR) mutations have been identified and these mutants are pathologically important, few theoretical studies have investigated the role of AR protein folding stability in disease and its relationship with the phenotype of the patients. Here, we extracted AR...

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Detalles Bibliográficos
Autores principales: Chen, Fangfang, Chen, Xiaoqing, Jiang, Fan, Leng, Feng, Liu, Wei, Gui, Yaoting, Yu, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7374729/
https://www.ncbi.nlm.nih.gov/pubmed/32694570
http://dx.doi.org/10.1038/s41598-020-68731-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7374729/
https://www.ncbi.nlm.nih.gov/pubmed/32694570
http://dx.doi.org/10.1038/s41598-020-68731-7

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