Comparison of the Base Excision and Direct Reversal Repair Pathways for Correcting 1,N(6)-Ethenoadenine in Strongly Positioned Nucleosome Core Particles

[Image: see text] 1,N(6)-ethenoadenine (εA) is a mutagenic lesion and biomarker observed in numerous cancerous tissues. Two pathways are responsible for its repair: base excision repair (BER) and direct reversal repair (DRR). Alkyladenine DNA glycosylase (AAG) is the primary enzyme that excises εA i...

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Detalles Bibliográficos
Autores principales: Caffrey, Paul J., Kher, Raadhika, Bian, Ke, Li, Deyu, Delaney, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7374743/
https://www.ncbi.nlm.nih.gov/pubmed/32293880
http://dx.doi.org/10.1021/acs.chemrestox.0c00089

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7374743/
https://www.ncbi.nlm.nih.gov/pubmed/32293880
http://dx.doi.org/10.1021/acs.chemrestox.0c00089

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