Cargando…

Cancer cells grown in 3D under fluid flow exhibit an aggressive phenotype and reduced responsiveness to the anti-cancer treatment doxorubicin

3D laboratory models of cancer are designed to recapitulate the biochemical and biophysical characteristics of the tumour microenvironment and aim to enable studies of cancer, and new therapeutic modalities, in a physiologically-relevant manner. We have developed an in vitro 3D model comprising a ce...

Descripción completa

Detalles Bibliográficos
Autores principales: Azimi, Tayebeh, Loizidou, Marilena, Dwek, Miriam V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7374750/
https://www.ncbi.nlm.nih.gov/pubmed/32694700
http://dx.doi.org/10.1038/s41598-020-68999-9