Small extracellular vesicles secreted by human iPSC-derived MSC enhance angiogenesis through inhibiting STAT3-dependent autophagy in ischemic stroke

BACKGROUND: Small extracellular vesicles (sEV) secreted by mesenchymal stem cells (MSC) derived from human induced pluripotent stem cells (iPSC, iMSC-sEV) are considered to have great potential in treating ischemic diseases. Angiogenesis play an important role in post-stroke recovery. However, no st...

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Detalles Bibliográficos
Autores principales: Xia, Yuguo, Ling, Xiaozheng, Hu, Guowen, Zhu, Qingwei, Zhang, Juntao, Li, Qing, Zhao, Bizeng, Wang, Yang, Deng, Zhifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7374834/
https://www.ncbi.nlm.nih.gov/pubmed/32698909
http://dx.doi.org/10.1186/s13287-020-01834-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7374834/
https://www.ncbi.nlm.nih.gov/pubmed/32698909
http://dx.doi.org/10.1186/s13287-020-01834-0

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