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Formation and optimization of three-dimensional organoids generated from urine-derived stem cells for renal function in vitro

BACKGROUND: Organoids play an important role in basic research, drug screening, and regenerative medicine. Here, we aimed to develop a novel kind of three-dimensional (3D) organoids generated from urine-derived stem cells (USCs) and to explore whether kidney-specific extracellular matrix (kECM) coul...

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Detalles Bibliográficos
Autores principales: Sun, Guoliang, Ding, Beichen, Wan, Meimei, Chen, Liang, Jackson, John, Atala, Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7374873/
https://www.ncbi.nlm.nih.gov/pubmed/32698872
http://dx.doi.org/10.1186/s13287-020-01822-4