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Elevated serum levels of checkpoint molecules in patients with adult Still’s disease

BACKGROUND: The interaction between galectin-9 (Gal-9) and its ligand, T cell immunoglobulin, and mucin-containing-molecule-3 (TIM-3), one of the coinhibitory receptors, transduce the inhibitory signaling to regulate immune responses. The dysregulated expression of checkpoint molecules has been repo...

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Detalles Bibliográficos
Autores principales: Fujita, Yuya, Asano, Tomoyuki, Matsumoto, Haruki, Matsuoka, Naoki, Temmoku, Jumpei, Sato, Shuzo, Furuya, Makiko Yashiro, Suzuki, Eiji, Watanabe, Hiroshi, Koga, Tomohiro, Kawakami, Atsushi, Migita, Kiyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7374897/
https://www.ncbi.nlm.nih.gov/pubmed/32698838
http://dx.doi.org/10.1186/s13075-020-02263-3