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Alternative methylation of intron motifs is associated with cancer-related gene expression in both canine mammary tumor and human breast cancer

BACKGROUND: Canine mammary tumor (CMT) has long been considered as a good animal model for human breast cancer (HBC) due to their pathological and biological similarities. However, only a few aspects of the epigenome have been explored in both HBC and CMT. Moreover, DNA methylation studies have main...

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Detalles Bibliográficos
Autores principales: Nam, A-Reum, Lee, Kang-Hoon, Hwang, Hyeon-Ji, Schabort, Johannes J., An, Jae-Hoon, Won, Sung-Ho, Cho, Je-Yoel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7374976/
https://www.ncbi.nlm.nih.gov/pubmed/32693820
http://dx.doi.org/10.1186/s13148-020-00888-4