Evaluation of changes in cytochrome P450 2C19 activity in type 2 diabetic rats before and after treatment, by using isolated perfused liver model

OBJECTIVE(S): Alteration in drug metabolism is very likely in diabetes mellitus. This study assessed changes in CYP2C19 enzymatic activity in the liver using omeprazole as a probe in the animal model of type II diabetes (T2DM) before and after treatment with metformin and cinnamon. MATERIALS AND MET...

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Detalles Bibliográficos
Autores principales: Neyshaburinezhad, Navid, Rouini, Mohammad Reza, Entezari, Hanieh, Lavasani, Hoda, Hosseinzadeh Ardakani, Yalda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7374996/
https://www.ncbi.nlm.nih.gov/pubmed/32742601
http://dx.doi.org/10.22038/ijbms.2020.40836.9642

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7374996/
https://www.ncbi.nlm.nih.gov/pubmed/32742601
http://dx.doi.org/10.22038/ijbms.2020.40836.9642

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