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Autocrine C‐peptide protects INS1 β cells against palmitic acid‐induced oxidative stress in peroxisomes by inducing catalase
AIMS: C‐peptide, produced by pancreatic β cells and co‐secreted in the bloodstream with insulin, has antioxidant properties in glucose‐ and hydrogen peroxide (H(2)O(2))‐exposed INS1 β cells. Palmitic acid, the most physiologically abundant long‐chain free fatty acid in humans, is metabolized in pero...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7375117/ https://www.ncbi.nlm.nih.gov/pubmed/32704568 http://dx.doi.org/10.1002/edm2.147 |