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Autocrine C‐peptide protects INS1 β cells against palmitic acid‐induced oxidative stress in peroxisomes by inducing catalase

AIMS: C‐peptide, produced by pancreatic β cells and co‐secreted in the bloodstream with insulin, has antioxidant properties in glucose‐ and hydrogen peroxide (H(2)O(2))‐exposed INS1 β cells. Palmitic acid, the most physiologically abundant long‐chain free fatty acid in humans, is metabolized in pero...

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Detalles Bibliográficos
Autores principales:	Luppi, Patrizia, Drain, Nicholas, To, Ramsey, Stolz, Donna, Wallace, Callen, Watkins, Simon, Drain, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Original Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7375117/ https://www.ncbi.nlm.nih.gov/pubmed/32704568 http://dx.doi.org/10.1002/edm2.147

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