Insights Into the Mechanism of MCT8 Oligomerization

Mutations in the thyroid hormone transporter monocarboxylate transporter 8 (MCT8) result in MCT8 deficiency, characterized by severe intellectual and motor disability. The MCT8 protein is predicted to have 12 transmembrane domains (TMDs) and is expressed as monomers, homodimers, and homo-oligomers....

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Detalles Bibliográficos
Autores principales: Groeneweg, Stefan, van den Berge, Amanda, Lima de Souza, Elaine C, Meima, Marcel E, Peeters, Robin P, Visser, W Edward
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7375341/
https://www.ncbi.nlm.nih.gov/pubmed/32724870
http://dx.doi.org/10.1210/jendso/bvaa080

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7375341/
https://www.ncbi.nlm.nih.gov/pubmed/32724870
http://dx.doi.org/10.1210/jendso/bvaa080

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