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Remote Ischemic Pre-Conditioning Attenuates Adverse Cardiac Remodeling and Mortality Following Doxorubicin Administration in Mice

OBJECTIVES: Because of its multifaceted cardioprotective effects, remote ischemic pre-conditioning (RIPC) was examined as a strategy to attenuate doxorubicin (DOX) cardiotoxicity. BACKGROUND: The use of DOX is limited by dose-dependent cardiotoxicity and heart failure. Oxidative stress, mitochondria...

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Detalles Bibliográficos
Autores principales: Gertz, Zachary M., Cain, Chad, Kraskauskas, Donatas, Devarakonda, Teja, Mauro, Adolfo G., Thompson, Jeremy, Samidurai, Arun, Chen, Qun, Gordon, Sarah W., Lesnefsky, Edward J., Das, Anindita, Salloum, Fadi N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7375406/
https://www.ncbi.nlm.nih.gov/pubmed/32699841
http://dx.doi.org/10.1016/j.jaccao.2019.11.004