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Remote Ischemic Pre-Conditioning Attenuates Adverse Cardiac Remodeling and Mortality Following Doxorubicin Administration in Mice
OBJECTIVES: Because of its multifaceted cardioprotective effects, remote ischemic pre-conditioning (RIPC) was examined as a strategy to attenuate doxorubicin (DOX) cardiotoxicity. BACKGROUND: The use of DOX is limited by dose-dependent cardiotoxicity and heart failure. Oxidative stress, mitochondria...
Autores principales: | Gertz, Zachary M., Cain, Chad, Kraskauskas, Donatas, Devarakonda, Teja, Mauro, Adolfo G., Thompson, Jeremy, Samidurai, Arun, Chen, Qun, Gordon, Sarah W., Lesnefsky, Edward J., Das, Anindita, Salloum, Fadi N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7375406/ https://www.ncbi.nlm.nih.gov/pubmed/32699841 http://dx.doi.org/10.1016/j.jaccao.2019.11.004 |
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