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Suppression of cardiomyocyte functions by β-CTX isolated from the Thai king cobra (Ophiophagus hannah) venom via an alternative method

BACKGROUND: Beta-cardiotoxin (β-CTX), the three-finger toxin isolated from king cobra (Ophiophagus hannah) venom, possesses β-blocker activity as indicated by its negative chronotropy and its binding property to both β-1 and β-2 adrenergic receptors and has been proposed as a novel β-blocker candida...

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Detalles Bibliográficos
Autores principales: Lertwanakarn, Tuchakorn, Suntravat, Montamas, Sanchez, Elda E., Boonhoh, Worakan, Solaro, R. John, Wolska, Beata M., Martin, Jody L., de Tombe, Pieter P., Tachampa, Kittipong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centro de Estudos de Venenos e Animais Peçonhentos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7375408/
https://www.ncbi.nlm.nih.gov/pubmed/32742278
http://dx.doi.org/10.1590/1678-9199-JVATITD-2020-0005