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Inhibitors of metalloprotease, γ-sectretase, protein kinase C and Rho kinase inhibit wild-type adenoviral replication

Adenoviruses cause upper respiratory infections, conjunctivitis, keratitis, and gastrointestinal illness. These can be fatal in immunocompromised individuals. Adenoviruses have also been engineered into viral vectors to deliver therapeutic genes or induce immunity as vaccine carriers. The success of...

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Detalles Bibliográficos
Autores principales: Liu, Alice, Ildefonso, Cristhian J., Bond, Wesley S., Hurwitz, Mary Y., Hurwitz, Richard L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7375579/
https://www.ncbi.nlm.nih.gov/pubmed/32697798
http://dx.doi.org/10.1371/journal.pone.0236175