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AncesTree: An interactive immunoglobulin lineage tree visualizer

High-throughput sequencing of human immunoglobulin genes allows analysis of antibody repertoires and the reconstruction of clonal lineage evolution. The study of antibodies (Abs) affinity maturation is of specific interest to understand the generation of Abs with high affinity or broadly neutralizin...

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Detalles Bibliográficos
Autores principales: Foglierini, Mathilde, Pappas, Leontios, Lanzavecchia, Antonio, Corti, Davide, Perez, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7375605/
https://www.ncbi.nlm.nih.gov/pubmed/32649725
http://dx.doi.org/10.1371/journal.pcbi.1007731