Whole cell biophysical modeling of codon-tRNA competition reveals novel insights related to translation dynamics

The importance of mRNA translation models has been demonstrated across many fields of science and biotechnology. However, a whole cell model with codon resolution and biophysical dynamics is still lacking. We describe a whole cell model of translation for E. coli. The model simulates all major trans...

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Detalles Bibliográficos
Autores principales: Levin, Doron, Tuller, Tamir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7375613/
https://www.ncbi.nlm.nih.gov/pubmed/32649657
http://dx.doi.org/10.1371/journal.pcbi.1008038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7375613/
https://www.ncbi.nlm.nih.gov/pubmed/32649657
http://dx.doi.org/10.1371/journal.pcbi.1008038

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