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Whole cell biophysical modeling of codon-tRNA competition reveals novel insights related to translation dynamics
The importance of mRNA translation models has been demonstrated across many fields of science and biotechnology. However, a whole cell model with codon resolution and biophysical dynamics is still lacking. We describe a whole cell model of translation for E. coli. The model simulates all major trans...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7375613/ https://www.ncbi.nlm.nih.gov/pubmed/32649657 http://dx.doi.org/10.1371/journal.pcbi.1008038 |