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Longitudinal HER2 amplification tracked in circulating tumor DNA for therapeutic effect monitoring and prognostic evaluation in patients with breast cancer

BACKGROUND: Human epidermal growth factor receptor 2(HER2) status is a crucial predictive factor for prognostic assessment and targeted therapy selection, which may be influenced by intratumor heterogeneity and molecular divergence between the primary site and different metastases. Therefore, we per...

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Detalles Bibliográficos
Autores principales: Guan, Xiuwen, Liu, Binliang, Niu, Yunyun, Dong, Xin, Zhu, Xia, Li, Chunxiao, Li, Lixi, Yi, Zongbi, Sun, Xiaoying, Chen, Hongyan, Lu, Sijia, Ma, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7375665/
https://www.ncbi.nlm.nih.gov/pubmed/31927339
http://dx.doi.org/10.1016/j.breast.2019.12.010