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PPM1D Knockdown Suppresses Cell Proliferation, Promotes Cell Apoptosis, and Activates p38 MAPK/p53 Signaling Pathway in Acute Myeloid Leukemia

OBJECTIVES: This study was to explore the effect of protein phosphatase, Mg(2+)/Mn(2+) dependent 1D knockdown on proliferation and apoptosis as well as p38 MAPK/p53 signaling pathway in acute myeloid leukemia. METHODS: The expression of protein phosphatase, Mg(2+)/Mn(2+) dependent 1D was detected in...

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Detalles Bibliográficos
Autores principales: Li, Bin, Hu, Jie, He, Di, Chen, Qi, Liu, Suna, Zhu, Xiaoling, Yu, Meijia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7375723/
https://www.ncbi.nlm.nih.gov/pubmed/32691668
http://dx.doi.org/10.1177/1533033820942312