TBR-760, a Dopamine-Somatostatin Compound, Arrests Growth of Aggressive Nonfunctioning Pituitary Adenomas in Mice

TBR-760 (formerly BIM-23A760) is a chimeric dopamine (DA)-somatostatin (SST) compound with potent agonist activity at both DA type 2 (D2R) and SST type 2 (SSTR2) receptors. Studies have shown that chimeric DA-SST compounds are more efficacious than individual DA and/or SST analogues, either alone or...

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Detalles Bibliográficos
Autores principales: Halem, Heather A, Hochgeschwender, Ute, Rih, Jeong Keun, Nelson, Richard, Johnson, G Allan, Thiagalingam, Arunthi, Culler, Michael D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7375803/
https://www.ncbi.nlm.nih.gov/pubmed/32591776
http://dx.doi.org/10.1210/endocr/bqaa101

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7375803/
https://www.ncbi.nlm.nih.gov/pubmed/32591776
http://dx.doi.org/10.1210/endocr/bqaa101

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