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Molecular determinants of large cargo transport into the nucleus

Nucleocytoplasmic transport is tightly regulated by the nuclear pore complex (NPC). Among the thousands of molecules that cross the NPC, even very large (>15 nm) cargoes such as pathogens, mRNAs and pre-ribosomes can pass the NPC intact. For these cargoes, there is little quantitative understandi...

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Detalles Bibliográficos
Autores principales: Paci, Giulia, Zheng, Tiantian, Caria, Joana, Zilman, Anton, Lemke, Edward A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7375812/
https://www.ncbi.nlm.nih.gov/pubmed/32692309
http://dx.doi.org/10.7554/eLife.55963