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3,6’-dithiopomalidomide reduces neural loss, inflammation, behavioral deficits in brain injury and microglial activation

Traumatic brain injury (TBI) causes mortality and disability worldwide. It can initiate acute cell death followed by secondary injury induced by microglial activation, oxidative stress, inflammation and autophagy in brain tissue, resulting in cognitive and behavioral deficits. We evaluated a new pom...

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Detalles Bibliográficos
Autores principales: Lin, Chih-Tung, Lecca, Daniela, Yang, Ling-Yu, Luo, Weiming, Scerba, Michael T, Tweedie, David, Huang, Pen-Sen, Jung, Yoo-Jin, Kim, Dong Seok, Yang, Chih-Hao, Hoffer, Barry J, Wang, Jia-Yi, Greig, Nigel H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7375814/
https://www.ncbi.nlm.nih.gov/pubmed/32589144
http://dx.doi.org/10.7554/eLife.54726