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Controlling protein function by fine-tuning conformational flexibility

In a living cell, protein function is regulated in several ways, including post-translational modifications (PTMs), protein-protein interaction, or by the global environment (e.g. crowding or phase separation). While site-specific PTMs act very locally on the protein, specific protein interactions t...

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Detalles Bibliográficos
Autores principales: Schmid, Sonja, Hugel, Thorsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7375816/
https://www.ncbi.nlm.nih.gov/pubmed/32697684
http://dx.doi.org/10.7554/eLife.57180