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Switching the intracellular pathway and enhancing the therapeutic efficacy of small interfering RNA by auroliposome
Gene silencing using small-interfering RNA (siRNA) is a viable therapeutic approach; however, the lack of effective delivery systems limits its clinical translation. Herein, we doped conventional siRNA-liposomal formulations with gold nanoparticles to create “auroliposomes,” which significantly enha...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7375829/ https://www.ncbi.nlm.nih.gov/pubmed/32743073 http://dx.doi.org/10.1126/sciadv.aba5379 |