A somatic evolutionary model of the dynamics of aneuploid cells during hematopoietic reconstitution

Aneuploidy is a feature of many cancers. Recent studies demonstrate that in the hematopoietic stem and progenitor cell (HSPC) compartment aneuploid cells have reduced fitness and are efficiently purged from the bone marrow. However, early phases of hematopoietic reconstitution following bone marrow...

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Detalles Bibliográficos
Autores principales: Rozhok, Andrii I., Silberman, Rebecca E., Higa, Kelly C., Liggett, L. Alex, Amon, Angelika, DeGregori, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376010/
https://www.ncbi.nlm.nih.gov/pubmed/32699207
http://dx.doi.org/10.1038/s41598-020-68729-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376010/
https://www.ncbi.nlm.nih.gov/pubmed/32699207
http://dx.doi.org/10.1038/s41598-020-68729-1

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