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Validation of a stroke model in rat compatible with rt-PA-induced thrombolysis: new hope for successful translation to the clinic

The recent clinical trial (DAWN) suggests that recanalization treatment may be beneficial up to 24 h after stroke onset, thus re-opening avenues for development of new therapeutic strategies. Unfortunately, there is a continuous failure of drugs in clinical trials and one of the major reasons propos...

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Detalles Bibliográficos
Autores principales: Arkelius, Kajsa, Vivien, Denis, Orset, Cyrille, Ansar, Saema
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376012/
https://www.ncbi.nlm.nih.gov/pubmed/32699371
http://dx.doi.org/10.1038/s41598-020-69081-0