Cargando…
Validation of a stroke model in rat compatible with rt-PA-induced thrombolysis: new hope for successful translation to the clinic
The recent clinical trial (DAWN) suggests that recanalization treatment may be beneficial up to 24 h after stroke onset, thus re-opening avenues for development of new therapeutic strategies. Unfortunately, there is a continuous failure of drugs in clinical trials and one of the major reasons propos...
Autores principales: | Arkelius, Kajsa, Vivien, Denis, Orset, Cyrille, Ansar, Saema |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376012/ https://www.ncbi.nlm.nih.gov/pubmed/32699371 http://dx.doi.org/10.1038/s41598-020-69081-0 |
Ejemplares similares
-
Combination treatment with U0126 and rt-PA prevents adverse effects of the delayed rt-PA treatment after acute ischemic stroke
por: Orset, Cyrille, et al.
Publicado: (2021) -
Repair-related molecular changes during recovery phase of ischemic stroke in female rats
por: Mostajeran, Maryam, et al.
Publicado: (2022) -
Intravenous thrombolysis with rt-PA in stroke: experience of the moroccan stroke unit
por: Chtaou, Naima, et al.
Publicado: (2016) -
Pro-Inflammatory Mediators and Apoptosis Correlate to rt-PA Response in a Novel Mouse Model of Thromboembolic Stroke
por: Ansar, Saema, et al.
Publicado: (2014) -
Successful systemic thrombolysis with rtPA in a patient with history of a life-threatening rtPA-associated orolingual angioedema
por: Pelz, Johann Otto, et al.
Publicado: (2017)