B cell zone reticular cell microenvironments shape CXCL13 gradient formation

Through the formation of concentration gradients, morphogens drive graded responses to extracellular signals, thereby fine-tuning cell behaviors in complex tissues. Here we show that the chemokine CXCL13 forms both soluble and immobilized gradients. Specifically, CXCL13(+) follicular reticular cells...

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Detalles Bibliográficos
Autores principales: Cosgrove, Jason, Novkovic, Mario, Albrecht, Stefan, Pikor, Natalia B., Zhou, Zhaoukun, Onder, Lucas, Mörbe, Urs, Cupovic, Jovana, Miller, Helen, Alden, Kieran, Thuery, Anne, O’Toole, Peter, Pinter, Rita, Jarrett, Simon, Taylor, Emily, Venetz, Daniel, Heller, Manfred, Uguccioni, Mariagrazia, Legler, Daniel F., Lacey, Charles J., Coatesworth, Andrew, Polak, Wojciech G., Cupedo, Tom, Manoury, Bénedicte, Thelen, Marcus, Stein, Jens V., Wolf, Marlene, Leake, Mark C., Timmis, Jon, Ludewig, Burkhard, Coles, Mark C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376062/
https://www.ncbi.nlm.nih.gov/pubmed/32699279
http://dx.doi.org/10.1038/s41467-020-17135-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376062/
https://www.ncbi.nlm.nih.gov/pubmed/32699279
http://dx.doi.org/10.1038/s41467-020-17135-2

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