The perplexity of targeting genetic alterations in hepatocellular carcinoma

Genetic heterogeneity is a well-recognized feature of hepatocellular carcinoma (HCC). The coexistence of multiple genetic alterations in the same HCC nodule contributes to explain why gene-targeted therapy has largely failed. Targeting of early genetic alterations could theoretically be a more effec...

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Detalles Bibliográficos
Autores principales: Barone, Michele, Di Leo, Alfredo, Sabbà, Carlo, Mazzocca, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Perspectives in Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376083/
https://www.ncbi.nlm.nih.gov/pubmed/32699957
http://dx.doi.org/10.1007/s12032-020-01392-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376083/
https://www.ncbi.nlm.nih.gov/pubmed/32699957
http://dx.doi.org/10.1007/s12032-020-01392-8

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