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Increased blood COASY DNA methylation levels a potential biomarker for early pathology of Alzheimer’s disease

Early diagnosis of dementia including Alzheimer’s disease (AD) is an urgent medical and welfare issue. However, to date, no simple biometrics have been available. We reported that blood DNA methylation levels of the COASY gene, which encodes coenzyme A synthase, were increased in individuals with AD...

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Detalles Bibliográficos
Autores principales: Kobayashi, Nobuyuki, Shinagawa, Shunichiro, Niimura, Hidehito, Kida, Hisashi, Nagata, Tomoyuki, Tagai, Kenji, Shimada, Kazuya, Oka, Naomi, Shikimoto, Ryo, Noda, Yoshihiro, Nakajima, Shinichiro, Mimura, Masaru, Shigeta, Masahiro, Kondo, Kazuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376092/
https://www.ncbi.nlm.nih.gov/pubmed/32699290
http://dx.doi.org/10.1038/s41598-020-69248-9