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The Glycosphingolipid GM3 Modulates Conformational Dynamics of the Glucagon Receptor
The extracellular domain (ECD) of class B1 G-protein-coupled receptors (GPCRs) plays a central role in signal transduction and is uniquely positioned to sense both the extracellular and membrane environments. Although recent studies suggest a role for membrane lipids in the modulation of class A and...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Biophysical Society
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376093/ https://www.ncbi.nlm.nih.gov/pubmed/32610088 http://dx.doi.org/10.1016/j.bpj.2020.06.009 |