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Observing Protein Degradation by the PAN-20S Proteasome by Time-Resolved Neutron Scattering
The proteasome is a key player of regulated protein degradation in all kingdoms of life. Although recent atomic structures have provided snapshots on a number of conformations, data on substrate states and populations during the active degradation process in solution remain scarce. Here, we use time...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Biophysical Society
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376118/ https://www.ncbi.nlm.nih.gov/pubmed/32640186 http://dx.doi.org/10.1016/j.bpj.2020.06.015 |