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Inhibition of NADPH oxidase alleviates germ cell apoptosis and ER stress during testicular ischemia reperfusion injury

Testicular torsion and detorsion (TTD) is a serious urological condition affecting young males that is underlined by an ischemia reperfusion injury (tIRI) to the testis as the pathophysiological mechanism. During tIRI, uncontrolled production of oxygen reactive species (ROS) causes DNA damage leadin...

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Detalles Bibliográficos
Autores principales: Al-Saleh, Farah, Khashab, Farah, Fadel, Fatemah, Al-Kandari, Nora, Al-Maghrebi, May
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376125/
https://www.ncbi.nlm.nih.gov/pubmed/32714044
http://dx.doi.org/10.1016/j.sjbs.2020.04.024