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Mendelian randomization implies no direct causal association between leukocyte telomere length and amyotrophic lateral sclerosis

We employed Mendelian randomization (MR) to evaluate the causal relationship between leukocyte telomere length (LTL) and amyotrophic lateral sclerosis (ALS) with summary statistics from genome-wide association studies (n = ~ 38,000 for LTL and ~ 81,000 for ALS in the European population; n = ~ 23,00...

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Detalles Bibliográficos
Autores principales: Gao, Yixin, Wang, Ting, Yu, Xinghao, Zhao, Huashuo, Zeng, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376149/
https://www.ncbi.nlm.nih.gov/pubmed/32699404
http://dx.doi.org/10.1038/s41598-020-68848-9