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Promoting crystallization of intrinsic membrane proteins with conjugated micelles

A new technique for promoting nucleation and growth of membrane protein (MP) crystals from micellar environments is reported. It relies on the conjugation of micelles that sequester MPs in protein detergent complexes (PDCs). Conjugation via amphiphilic [metal:chelator] complexes presumably takes pla...

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Detalles Bibliográficos
Autores principales: Van Truong, Thien, Ghosh, Mihir, Wachtel, Ellen, Friedman, Noga, Jung, Kwang-Hwan, Sheves, Mordechai, Patchornik, Guy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376161/
https://www.ncbi.nlm.nih.gov/pubmed/32699228
http://dx.doi.org/10.1038/s41598-020-68689-6