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Promoting crystallization of intrinsic membrane proteins with conjugated micelles
A new technique for promoting nucleation and growth of membrane protein (MP) crystals from micellar environments is reported. It relies on the conjugation of micelles that sequester MPs in protein detergent complexes (PDCs). Conjugation via amphiphilic [metal:chelator] complexes presumably takes pla...
Autores principales: | Van Truong, Thien, Ghosh, Mihir, Wachtel, Ellen, Friedman, Noga, Jung, Kwang-Hwan, Sheves, Mordechai, Patchornik, Guy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376161/ https://www.ncbi.nlm.nih.gov/pubmed/32699228 http://dx.doi.org/10.1038/s41598-020-68689-6 |
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