Monocytes from infliximab-resistant patients with Crohn’s disease exhibit a disordered cytokine profile

Crohn's disease (CD) is a chronic inflammatory disorder characterized by immune response dysregulation. Tumor necrosis factor-α (TNFα) is a key cytokine in the pathogenesis of CD, as indicated by the efficacy of anti-TNF-α therapy with infliximab (IFX). However, approximately 30–40% of CD patie...

Descripción completa

Detalles Bibliográficos
Autores principales: Gaiani, Federica, Rotoli, Bianca Maria, Ferrari, Francesca, Barilli, Amelia, Visigalli, Rossana, Carra, Maria Clotilde, de’Angelis, Gian Luigi, de’Angelis, Nicola, Dall’Asta, Valeria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376177/
https://www.ncbi.nlm.nih.gov/pubmed/32699266
http://dx.doi.org/10.1038/s41598-020-68993-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376177/
https://www.ncbi.nlm.nih.gov/pubmed/32699266
http://dx.doi.org/10.1038/s41598-020-68993-1

Ejemplares similares