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β-Carboline copper complex as a potential mitochondrial-targeted anticancer chemotherapeutic agent: Favorable attenuation of human breast cancer MCF7 cells via apoptosis

The development of preferentially selective cancer chemotherapeutics is a new trend in drug research. Thus, we designed and synthesized novel ternary complexes, [Cu(tryp)(Hnor)(2)(DMSO)]NO(3) (1) and [Zn(tryp)(Hnor)(2)(DMSO)]NO(3)(2) (tryp = DL-Tryptophane; Hnor = Norharmane, β-carboline; DMSO = Dim...

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Detalles Bibliográficos
Autores principales: Khan, Rais Ahmad, Khan, Mohammad Rashid, Usman, Mohammad, Sayeed, Fatima, Alghamdi, Huda A., Alrumman, Sulaiman, Alharbi, Walaa, Farshori, Nida N., Al-Oqail, Mai M., Siddiqui, Mohd. Rafiq, Khanjer, Maymonah Abu, Alsalme, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376190/
https://www.ncbi.nlm.nih.gov/pubmed/32714043
http://dx.doi.org/10.1016/j.sjbs.2020.05.001