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β-Carboline copper complex as a potential mitochondrial-targeted anticancer chemotherapeutic agent: Favorable attenuation of human breast cancer MCF7 cells via apoptosis
The development of preferentially selective cancer chemotherapeutics is a new trend in drug research. Thus, we designed and synthesized novel ternary complexes, [Cu(tryp)(Hnor)(2)(DMSO)]NO(3) (1) and [Zn(tryp)(Hnor)(2)(DMSO)]NO(3)(2) (tryp = DL-Tryptophane; Hnor = Norharmane, β-carboline; DMSO = Dim...
Autores principales: | Khan, Rais Ahmad, Khan, Mohammad Rashid, Usman, Mohammad, Sayeed, Fatima, Alghamdi, Huda A., Alrumman, Sulaiman, Alharbi, Walaa, Farshori, Nida N., Al-Oqail, Mai M., Siddiqui, Mohd. Rafiq, Khanjer, Maymonah Abu, Alsalme, Ali |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376190/ https://www.ncbi.nlm.nih.gov/pubmed/32714043 http://dx.doi.org/10.1016/j.sjbs.2020.05.001 |
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