Unique genomic and neoepitope landscapes across tumors: a study across time, tissues, and space within a single lynch syndrome patient

Lynch syndrome (LS) arises in patients with pathogenic germline variants in DNA mismatch repair genes. LS is the most common inherited cancer predisposition condition and confers an elevated lifetime risk of multiple cancers notably colorectal and endometrial carcinomas. A distinguishing feature of...

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Detalles Bibliográficos
Autores principales: Phung, Tanya N., Lenkiewicz, Elizabeth, Malasi, Smriti, Sharma, Amit, Anderson, Karen S., Wilson, Melissa A., Pockaj, Barbara A., Barrett, Michael T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376229/
https://www.ncbi.nlm.nih.gov/pubmed/32699259
http://dx.doi.org/10.1038/s41598-020-68939-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376229/
https://www.ncbi.nlm.nih.gov/pubmed/32699259
http://dx.doi.org/10.1038/s41598-020-68939-7

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