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Inhibitory effects of tangeretin and trans-ethyl caffeate on the HMG-CoA reductase activity: Potential agents for reducing cholesterol levels

One of the pathways to reduce cholesterol production in the liver is through the inhibition of HMG-Coa reductase (HMGCR) by current drugs, statins. However, these have side effects if consumed in prolonged periods. Tangeretin and trans-ethyl caffeate as alternative drugs in reducing hypercholesterol...

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Detalles Bibliográficos
Autores principales: Pangestika, Inten, Oksal, Efriyana, Tengku Muhammad, Tengku Sifzizul, Amir, Hermansyah, Syamsumir, Desy Fitrya, Wahid, Mohd Effendy Abdul, Andriani, Yosie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376234/
https://www.ncbi.nlm.nih.gov/pubmed/32714018
http://dx.doi.org/10.1016/j.sjbs.2020.06.010