Murine models of IDH-wild-type glioblastoma exhibit spatial segregation of tumor initiation and manifestation during evolution

Recent characterization of spatiotemporal genomic architecture of IDH-wild-type multifocal glioblastomas (M-GBMs) suggests a clinically unobserved common-ancestor (CA) with a less aggressive phenotype, generating highly genetically divergent malignant gliomas/GBMs in distant brain regions. Using ser...

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Detalles Bibliográficos
Autores principales: Li, Yinghua, Li, Bo, Li, Wei, Wang, Yuan, Akgül, Seçkin, Treisman, Daniel M., Heist, Kevin A., Pierce, Brianna R., Hoff, Benjamin, Ho, Cheng-Ying, Ferguson, David O., Rehemtulla, Alnawaz, Zheng, Siyuan, Ross, Brian D., Li, Jun Z., Zhu, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376246/
https://www.ncbi.nlm.nih.gov/pubmed/32699356
http://dx.doi.org/10.1038/s41467-020-17382-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376246/
https://www.ncbi.nlm.nih.gov/pubmed/32699356
http://dx.doi.org/10.1038/s41467-020-17382-3

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