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Microenvironment-triggered dual-activation of a photosensitizer- fluorophore conjugate for tumor specific imaging and photodynamic therapy

Photodynamic therapy is attracting increasing attention, but how to increase its tumor-specificity remains a daunting challenge. Herein we report a theranostic probe (azo-PDT) that integrates pyropheophorbide α as a photosensitizer and a NIR fluorophore for tumor imaging. The two functionalities are...

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Detalles Bibliográficos
Autores principales: Wang, Chang, Wang, Shengdan, Wang, Yuan, Wu, Honghai, Bao, Kun, Sheng, Rong, Li, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376251/
https://www.ncbi.nlm.nih.gov/pubmed/32699340
http://dx.doi.org/10.1038/s41598-020-68847-w