Population Pharmacokinetics and Exposure–Response of Luspatercept, an Erythroid Maturation Agent, in Anemic Patients With Myelodysplastic Syndromes

Luspatercept is a recombinant fusion protein that enhances late‐stage erythroid maturation. This report describes the population pharmacokinetics and exposure–response relationship of luspatercept in 260 patients with anemia due to myelodysplastic syndromes. Luspatercept displayed linear and time‐in...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Nianhang, Kassir, Nastya, Laadem, Abderrahmane, Maxwell, Stephen E., Sriraman, Priya, Giuseppi, Ana Carolina, Ritland, Steve, Linde, Peter G., Budda, Balasubrahmanyam, Reynolds, Joseph G., Zhou, Simon, Palmisano, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376288/
https://www.ncbi.nlm.nih.gov/pubmed/32602651
http://dx.doi.org/10.1002/psp4.12521

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376288/
https://www.ncbi.nlm.nih.gov/pubmed/32602651
http://dx.doi.org/10.1002/psp4.12521

Ejemplares similares