The Actions and Mechanisms of P2X7R and p38 MAPK Activation in Mediating Bortezomib-Induced Neuropathic Pain

The proteasome inhibitor bortezomib (BTZ) is a potent first-line anticancer drug for multiple myeloma; nonetheless, it induced peripheral neuropathy. It has been suggested that many cytokines may play a role in mediating neuropathic pain, but the underlying molecular mechanism is not fully understoo...

Descripción completa

Detalles Bibliográficos
Autores principales: Guo, Yan, Xu, Xiaobo, Huang, Jingyi, Wang, Zhen, Li, Zhenzhong, Liu, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376423/
https://www.ncbi.nlm.nih.gov/pubmed/32733956
http://dx.doi.org/10.1155/2020/8143754

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376423/
https://www.ncbi.nlm.nih.gov/pubmed/32733956
http://dx.doi.org/10.1155/2020/8143754

Ejemplares similares